第5回有性生殖研究会のご案内

大串素雅子会員(大阪大学)より,掲題の件で連絡がありましたのでご案内いたします。
□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□■□□■
第5回有性生殖研究会のご案内
概要
有性生殖研究会では有性生殖にかかわる幅広い分野にまたがる研究内容についてのハイレベルな発表・討論を行う。有性生殖に関連する研究でありながら、生殖発生、性分化、減数分裂、受精、初期胚発生、生殖代謝・分泌、などこれまで細分化されていた異分野の研究者が一同に会する場を提供することにより、演者と聴衆との相互交流・情報交換の促進し、枠組みにとらわれない新しい有性生殖研究のコミュニティーに発展させることを目指す。今年度は前半新学術「全能性」公開シンポ、後半第5回有性生殖研究会の合同で開催する。
日時:2025年3月6(木) – 8 (土)   
会場:三島 国立遺伝学研究所 (オンラインハイブリッド)
開催形態: 第5回有性生殖研究会は、新学術領域「全能性」公開シンポジウムと連続合同開催で実施されます。
前半: 新学術「全能性」公開シンポジウム  3月6(木) 13:00 – 7(金) 12:00  
後半: 第5回有性生殖研究会  3月7(金) 13:00 – 8 (土) 16:00  
(合同懇親会 7(金) 19:00)
発表形式:招待演者の口頭発表(オンライン配信あり)とポスター発表(現地のみ)
申込締切:2024 年 1 月 17 日 (月)
参加申込: ホームページからお申し込み下さい。
1参加登録をしてください。
2 事務局より後日折り返し参加登録の方に、発表要旨提出についてご案内を致します。
学生・若手ポスター発表の旅費支援について
定員に達した時点で申込締切前に打ち切る場合がありますので、ご希望の方はお早めに参加登録時に入力してください。なお、遠方あるいはキャリアを考慮して優先度をつける場合や、旅費または宿泊の一部についての支援になる場合があります。
現地参加について
現地会場収容人数に制限がございます。メイン会場(講堂)近くのサテライト会場席での視聴となる場合があります。また参加登録数が上限を超えた場合には、オンライン視聴への振り替えとなる場合がありますことをご了承ください。
共催: 学術変革領域A「ゲノムモダリティ」「生殖ライフスパン」「細胞運命コード」, 新学術領域研究「全能性プログラム」, 国際先導研究次世代ART, AMED ASPIRE生殖医療未来開拓, CREST「バイオDX」, 熊本大学発生医学研究所, 大阪大学蛋白質研究所
協賛: セコム科学技術振興財団
第5回有性生殖研究会研究会事務局
今井裕紀子(国立遺伝学研究所)
大串素雅子(大阪大学医学系研究科)
石黒啓一郎 (熊本大学発生医学研究所) 
お問い合わせ:石黒研・福田 m-fukuda@kumamoto-u.ac.jp

“第5回有性生殖研究会のご案内” の続きを読む

朱士恩先生のご逝去について

菊地和弘理事より,訃報の連絡がありましたのでご案内いたします。
□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□■□□■
朱士恩先生のご逝去について
中国畜牧獣医学会動物繁殖分会の会長である田見暉(Tian Jianhu)教授より、同会名誉会長である朱士恩(Zhu Shi’en)教授が、2024年10月20日午前7時37分、北京のご自宅でご病気のため、68歳でご逝去されたとの訃報を受けました。
朱先生は、1989年に日本に来日され、高知大学の故葛西孫三郎先生のもとに留学され、愛媛大学連合農学研究科で博士号を取得されました。帰国後は中国農業大学で教鞭を執られております。また、長年にわたり、同会の事務局長ならびに会長を務められました。朱先生は、日本繁殖生物学会ならびに韓国動物繁殖学会の会員らとともに、中国・日本・韓国の国際交流シンポジウム(http://reproduction.jp/NewHP/international_04.html)の礎を築き、これら3カ国の動物繁殖に関する基礎研究と技術展開に関する交流に重要な貢献を果たされました。
謹んでご冥福をお祈りするとともに哀悼の意を表したいと存じます。
(公社)日本繁殖生物学会理事 菊地和弘
  

【日本生殖内分泌学会】 学会誌29巻(最新号)につきまして

日本生殖内分泌学会より,掲題の件で連絡がありましたのでご案内いたします。
□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□■□□■
日本繫殖生物学会 御中
平素よりお世話になっております。
「日本生殖内分泌学会」学会誌編集担当の谷口 と申します。
このたび関連学会様へ、当会理事より最新号(電子ジャーナル)のご一読配信依頼を受けましてメールさせていただきます。
毎号、「学術奨励賞受賞論文」をはじめ「REVIEW」「研究フロンティア」「Topics」など日々の研究成果をおまとめした論文、および各大学の「研究室紹介」で構成しております。
最新号29巻は添付にて、28巻以前は下記のURLよりご閲覧いただけます。
お忙しいところ大変恐縮ですが、ご一読いただけますと幸甚でございます。
今後ともよろしくお願い申し上げます。

高知大学農林海洋科学部農林資源科学科(動物生産学分野)教員(助教相当)公募のお知らせ

松川和嗣会員(高知大学)より,掲題の件で連絡がありましたのでご案内いたします。
□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□■□□■
【募集職種】助教
【人数】1名
【締切日】令和6年12月9日(月)17時必着
詳細については下記のURLをご参照ください。
【問い合わせ先】物部総務課総務係 E-mail:km03@kochi-u.ac.jp 宛にメールでお問い合わせください。

北里大学獣医学部 獣医学科教員(獣医臨床繁殖学 教授)公募のお知らせ

久留主志朗会員(北里大学)より,添付のとおり公募の案内がありましたのでお知らせいたします。
□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□□■□■□□■
大学名 北里大学獣医学部
募集内容 獣医臨床繁殖学研究室(教授)
締切り  12/2

JRD Vol. 70 (5) の発刊のお知らせ

JRD Vol. 70 (5) の発刊のお知らせ
SRD会員の皆様へ
 平素からThe Journal of Reproduction and Development (JRD) の刊行にご協力を頂き有難うございます。Vol. 70 (5) が発刊となりました。本号では11報の論文を寄稿していただきました。ご一読いただき,論文執筆の際にご活用いただけますようお願いいたします。
JRD編集委員長 原山 洋
JRD Vol. 70 (5)
Original Article
Dairy cow parity affects relationships among nutritional parameters in the blood of dams, umbilical cords, and calves and placental development at calving
Riku MASHIMO, Hanon OHBAN, Yuka KUMAZAKI, Sayaka ITO, Tomono KATAGIRI, Nobuyuki KUSABA, Chiho KAWASHIMA
Volume 70, Issue 5, Pages 264-271
Association between prepartum vaginal temperature changes and placenta expulsion time in Holstein dairy cattle
Miki SAKATANI, Kaiyu KUBOTA, Satoshi HAGA, Masafumi MIWA
Volume 70, Issue 5, Pages 272-278
Carnosine supplementation in cryopreservation solution improved frozen-thawed bovine embryo viability
Toshimichi ISHII, Kento MORI-KOBAYASHI, Sho NAKAMURA, Satoshi OHKURA, Shuichi MATSUYAMA
Volume 70, Issue 5, Pages 279-285
Autophagy in the corpus luteum correlates with tissue growth in pregnant rats
Yasuaki OISHI, Koji ASAKAWA, Yuri ISHIWATA, Shota OKA, Ryota TERASHIMA, Makoto SUGIYAMA, Keiichiro KIZAKI, Mitsumori KAWAMINAMI, Shiro KURUSU
Volume 70, Issue 5, Pages 286-295
Cover Story:
The temporally regulated function and structure of the corpus luteum (CL) are critical for the establishment, maintenance, and termination of pregnancy across various animal species. Oishi et al. found that autophagic activity in the rat CL fluctuates in correlation with tissue weight rather than progesterone (P4) production (Oishi et al., Autophagy in the corpus luteum correlates with tissue growth in pregnant rats. pp. 286–295). Their perturbation experiment using a chemical inhibitor suggests that autophagy contributes to increasing the size of luteal steroidogenic cells and precisely modulates their P4 secretion. The dual nature of autophagy, which controls cellular survival or death, may be implicated in the reciprocal regulation of luteal P4 secretion to determine the appropriate gestational length in species whose P4 production depends solely on CL.
Perilipin2 depletion causes lipid droplet enlargement in the ovarian corpus luteum in mice
Megumi IBAYASHI, Takayuki TATSUMI, Satoshi TSUKAMOTO
Volume 70, Issue 5, Pages 296-302
A polysaccharide gel made of gellan gum improves oocyte maturation and embryonic development in pigs
Shunsuke HARA, Koumei SHIRASUNA, Hisataka IWATA
Volume 70, Issue 5, Pages 303-308
Cpne1 deficiency preserves sperm motility under Ca2+ channel blockade
Qiang XIE, Hanbin ZHANG, Yuge ZHUANG, Jinsheng LIU, Zicong HUANG, Xiaoyuan ZHANG, Ke MA, Wenyuan LIU, Minyu XIE, Chuyu HUANG, Xiaojing ZHONG, Feilong CHEN, Feng ZOU, Wansong ZHANG, Chunming QIU, Canbiao SUN, Xiangjin KANG, Zhenguo CHEN, Guofei ZHANG
Volume 70, Issue 5, Pages 309-319
Kdm4d mutant mice show impaired sperm motility and subfertility
Zhuoran XU, Yuka FUJIMOTO, Mizuki SAKAMOTO, Daiyu ITO, Masahito IKAWA, Takashi ISHIUCHI
Volume 70, Issue 5, Pages 320-326
Central δ/κ opioid receptor signaling pathways mediate chronic and/or acute suckling-induced LH suppression in rats during late lactation
Yoshihisa UENOYAMA, Miku NONOGAKI, Hitomi TSUCHIDA, Marina TAKIZAWA, Sena MATSUZAKI, Naoko INOUE, Hiroko TSUKAMURA
Volume 70, Issue 5, Pages 327-337
Technology Report
Zinc transporter ZnT3/Slc30a3 has a potential role in zinc ion influx in mouse oocytes
Atsuko KAGEYAMA, Jumpei TERAKAWA, Shunsuke TAKARABE, Hibiki SUGITA, Yui KAWATA, Junya ITO, Naomi KASHIWAZAKI
Volume 70, Issue 5, Pages 338-342
Three-dimensional cell culture using CD9-positive cells isolated from marginal cell layer of intermediate lobe of rats sustains in vivo-like primary niche environment
Kotaro HORIGUCHI, Takehiro TSUKADA, Saishu YOSHIDA, Ken FUJIWARA, Takashi NAKAKURA, Morio AZUMA, Ayano SHINDO, Rumi HASEGAWA, Shu TAKIGAMI
Volume 70, Issue 5, Pages 343-347
——————————————————
JRD Vol. 70 (4)
SRD Young Investigator Award 2023
Molecular approaches to mammalian uterine receptivity for conceptus implantation
Kaiyu KUBOTA
Volume 70 Issue 4 Pages 207-212
Cover Story:
Uterine receptivity is the specific state during early pregnancy when the endometrium is ready to accept the embryo or conceptus, and this process by which the embryo attaches to the endometrium is also known as implantation. Kubota summarized the molecular mechanisms underlying steroid hormone-induced uterine receptivity and the similarities and differences in this mechanism among different mammals (Kubota K. Molecular approaches to mammalian uterine receptivity for conceptus implantation, pp. 207–212). This review will help understand the importance of uterine receptivity and the challenges associated with alleviating implantation failure. Investigating the mechanism of uterine receptivity is necessary to develop diagnostic and therapeutic tools for successful pregnancies.
Original Article
Alpha-synuclein expression in oxytocin neurons of young and old bovine brains
Yvan Bienvenu NIYONZIMA, Yuuki ASATO, Hiroya KADOKAWA
Volume 70 Issue 4 Pages 213-222
Excluding alanine from minimum essential medium (MEM) nonessential amino acid supplementation of the culture medium facilitates post-fertilization events and early cleavages of bovine oocytes fertilized in vitro
Nobuhiko ITAMI, Satoshi AKAGI, Yuji HIRAO
Volume 70 Issue 4 Pages 223-228
Oocyte activation with phospholipase Cζ mRNA induces repetitive intracellular Ca2+ rises and improves the quality of pig embryos after intracytoplasmic sperm injection
Michiko NAKAI, Shun-ichi SUZUKI, Dai-ichiro FUCHIMOTO, Shoichiro SEMBON, Kazuhiro KIKUCHI
Volume 70 Issue 4 Pages 229-237
Role and action mechanisms of tPA in CRH-induced apoptosis of mouse oviductal epithelial and mural granulosa cells
Yong-Qing YANG, Min ZHANG, Qi HUA, Rui-Jie MA, Xiao-Yan WANG, Hong-Jie YUAN, Ming-Jiu LUO, Jing-He TAN
Volume 70 Issue 4 Pages 238-246
Resveratrol intake by males increased the mitochondrial DNA copy number and telomere length of blastocysts derived from aged mice
Noko TERAMOTO, Yuri OKADA, Nao ABURADA, Masamune HAYASHI, Jun ITO, Komei SHIRASUNA, Hisataka IWATA
Volume 70 Issue 4 Pages 247-253
Technology Report
Lower developmental potential of rat zygotes produced by ooplasmic injection of testicular spermatozoa versus cauda epididymal spermatozoa
Misuzu IDE, Ibuki SAITO, Makoto SANBO, Mito KANATSU-SHINOHARA, Takashi SHINOHARA, Masumi HIRABAYASHI, Shinichi HOCHI
Volume 70 Issue 4 Pages 254-258
Evaluation of bovine embryo quality based on gene expression profiling using whole-transcriptome amplification
Takashi FUJII, Takamasa MUKAI, Shoji HASEGAWA, Toh-ichi HIRATA, Ken SAWAI
Volume 70 Issue 4 Pages 259-263
——————————————————
JRD Vol. 70 (3)
SRD Outstanding Research Award 2023
Role of chemokines in regulating luteal and uterine functions in pregnant cows
Ryosuke SAKUMOTO
Volume 70 Issue 3 Pages 145-151
Cover Story:
Chemokines are known to regulate various reproductive functions, such as regulation of corpus luteum (CL) and uterine functions in cows. However, the role of chemokines in pregnancy has not yet been fully elucidated. Sakumoto summarized and reviewed the literature on chemokine (-receptor) expression and its physiological roles in the bovine CL and uterus during pregnancy. This review will help understand the mechanisms of chemokine-mediated interactions among the CL, uterus, immune cells, and conceptus during pregnancy in cows.
SRD Young Investigator Award 2023
Chromatin structure in totipotent mouse early preimplantation embryos
Masatoshi OOGA
Volume 70 Issue 3 Pages 152-159
Original Article
Effect of ovarian stimulation on developmental speed of preimplantation embryo in a mouse model
Mayuko KURUMIZAKA, Tatsuma YAO, Mikiko TOKORO, Noritaka FUKUNAGA, Yoshimasa ASADA, Kazuo YAMAGATA
Volume 70 Issue 3 Pages 160-168
Lipopolysaccharide-binding protein in follicular fluid is associated with the follicular inflammatory status and granulosa cell steroidogenesis in dairy cows
Fumie MAGATA, Misato KIKUZAWA, Heinrich BOLLWEIN, Fuko MATSUDA, Shingo HANEDA
2024 Volume 70 Issue 3 Pages 169-176
Social effects on behaviorally-scored and pedometer-detected estrus in beef cattle
Hiromi KUSAKA, Minoru SAKAGUCHI
Volume 70 Issue 3 Pages 177-183
Physiological high temperatures alter the amino acid metabolism of bovine early antral follicles
Kohei KAWANO, Kenichiro SAKAGUCHI, Nattapong NINPETCH, Yojiro YANAGAWA, Seiji KATAGIR
Volume 70 Issue 3 Pages 184-191
Changes in interleukin-2, -4, -6 and -8 expression in the postovulatory sow endometrium after artificial insemination based on conceived or failed to conceive
Minami W. OKUYAMA, Masaharu MORIYOSHI, Seiji KATAGIRI
Volume 70 Issue 3 Pages 192-196
DNA repair is efficient in irradiated M phase zygotes
Yuan WANG, Dai TSUKIOKA, Shoji ODA, Hiroshi MITANI, Fugaku AOKI
Volume 70 Issue 3 Pages 197-201
Technology Report
Effect of globin peptide on female fertility in aging granulosa cell-specific Nrg1 knockout mice
Takashi UMEHARA, Marino OGASAHARA, D.M.V. Supun PREMARATHNE, Yuka SASAKAWA, Yasuo SUMIDA, Masayuki SHIMADA
Volume 70 Issue 3 Pages 202-206
——————————————————
JRD Vol. 70 (2)
Obituary (Special thanks)
In memory of Dr. Ryuzo Yanagimachi (Yana) (1928–2023)
Teruhiko WAKAYAMA, Atsuo OGURA
Volume 70 Issue 2 Pages i-iv
Original Article
Identification and characterization of dystrophin-locus-derived testis-specific protein: A testis-specific gene within the intronic region of the rat dystrophin gene
Keitaro YAMANOUCHI, Shizuka KATO, Yukie TANAKA, Masanari IKEDA, Yukina OSHIMO, Takanori SHIGA, Kei HATAMOTO, James CHAMBERS, Takuya IMAMURA, Ryuji HIRAMATSU, Kazuyuki UCHIDA, Fuko MATSUDA, Takashi MATSUWAKI, Tetsuya KOHSAKA
Volume 70 Issue 2 Pages 55-64
Effect of paternal aging and vitrification on mitochondrial DNA copy number and telomere length of mouse blastocysts
Nao ABURADA, Jun ITO, Yuki INOUE, Taiyo YAMAMOTO, Masamune HAYASHI, Noko TERAMOTO, Yuri OKADA, Yuichi KOSHIISHI, Koumei SHIRASUNA, Hisataka IWATA
Volume 70 Issue 2 Pages 65-71
Lipid droplets synthesized during luteinization are degraded after pregnancy
Junichiro MITSUI, Megumi IBAYASHI, Ryutaro AIZAWA, Tomonori ISHIKAWA, Naoyuki MIYASAKA, Satoshi TSUKAMOTO
Volume 70 Issue 2 Pages 72-81
Efficient derivation of embryonic stem cells and primordial germ cell-like cells in cattle
Atsushi SHIRASAWA, Masafumi HAYASHI, Mayumi SHONO, Atsushi IDETA, Takashi YOSHINO, Katsuhiko HAYASHI
Volume 70 Issue 2 Pages 82-95
Cover Story:
The process of inducing the germ cell lineage from pluripotent stem cells, referred to as in vitro gametogenesis, aids in comprehending the mechanisms involved in germ cell differentiation and offers an alternative source of gametes for reproduction. Shirasawa et al. have developed a novel method for robust induction of primordial germ cell-like cells (PGCLCs) from newly established bovine embryonic stem (bES) cells. After a 24-hour culture with bone morphogenetic protein 4 (BMP4), followed by a three-dimensional culture with BMP4 and chemicals modulating WNT signaling, bES cells exhibited positive expression for a set of primordial germ cell (PGC) markers, including PRDM1/BLIMP1, TFAP2C, and SOX17. These outcomes are anticipated to have practical implications for the development of stem cell-based reproductive technologies in cattle.
Progesterone and estradiol regulate sperm hyperactivation and in vitro fertilization success in mice
Miyu FUJIKURA, Masakatsu FUJINOKI
Volume 70 Issue 2 Pages 96-103
Busulfan administration replicated the characteristics of the epididymal initial segment observed in mice lacking testis-epididymis lumicrine signaling
Daiji KIYOZUMI
Volume 70 Issue 2 Pages 104-114
Parallel expression patterns of NR4A nuclear receptor family genes in the pituitary gland of proestrus rats
Ryota TERASHIMA, Daiki NAGAO, Masato IKEO, Keisuke MORIOKA, Titaree LAOHARATCHATATHANIN, Shiro KURUSU, Mitsumori KAWAMINAMI
Volume 70 Issue 2 Pages 115-122
Time elapsed between ovulation and insemination determines the quality of fertilized rat oocytes
Naomi NAKAGATA, Satohiro NAKAO, Nobuyuki MIKODA, Katsuma YAMAGA, Toru TAKEO
Volume 70 Issue 2 Pages 123-130
High-concentration bovine serum albumin enhances fertilization ability of cold-stored rat sperm
Katsuma YAMAGA, Satohiro NAKAO, Nobuyuki MIKODA, Jorge Mario SZTEIN, Naomi NAKAGATA, Toru TAKEO
Volume 70 Issue 2 Pages 131-137
The fertility of dairy heifers and cows is not influenced by the follicular wave of the ovulatory follicle
Javad MOHAMMADI, Mehdi AZARI, Mojtaba KAFI
Volume 70 Issue 2 Pages 138-143
——————————————————
JRD Vol. 70 (1)
Review
Improvements in in vitro spermatogenesis: oxygen concentration, antioxidants, tissue-form design, and space control
Takehiko OGAWA, Takafumi MATSUMURA, Tatsuma YAO, Hiroshi KIMURA, Kiyoshi HASHIMOTO, Yu ISHIKAWA-YAMAUCHI, Takuya SATO
Volume 70 Issue 1 Pages 1-9
Cover Story:
For the past century, achieving in vitro spermatogenesis has remained a difficult challenge for researchers. In 2011, Ogawa et al. successfully demonstrated in vitro spermatogenesis in mice using an organ culture method. However, extending this method to other species posed challenges for over a decade. In 2023, Ogawa’s team achieved in vitro spermatogenesis in rats by incorporating several critical modifications to enhance their original technique. This review presents a detailed analysis by Ogawa et al. comparing their method with natural in vivo conditions and other synthetic alternatives. They systematically explore the merits, limitations, and inherent constraints of the organ culture approach, delving into the specifics of medium composition, the principles of the gas-liquid interphase method, use of microfluidic devices, and innovation of the PDMS-ceiling method. Highlighting the challenges faced, including regulating oxygen concentration, managing tissue formation, and regulating culture space-control. The insights and novel concepts shared in this review are particularly valuable for those involved in culture or related disciplines, providing innovative content, and encouraging further exploration in this field.
Original Article
PABPN1L is required for maternal mRNA degradation after meiosis resumption
Chihiro EMORI, Mayo KODANI, Ferheen ABBASI, Masashi MORI, Masahito IKAWA
Volume 70 Issue 1 Pages 10-17
Lipid droplet formation is spatiotemporally regulated in oocytes during follicular development in mice
Ryutaro AIZAWA, Megumi IBAYASHI, Junichiro MITSUI, Satoshi TSUKAMOTO
Volume 70 Issue 1 Pages 18-24
Development of a fluorometric Cuboni test for the semi-quantitative measurement of urinary estrogen levels and pregnancy detection in mares
Kaede ODA, Maya YOSHIDA, Abdul Razaq IRSHAD, Tomomi KANAZAWA, Toru TAKAHASHI
Volume 70 Issue 1 Pages 25-29
Equine chorionic gonadotropin treatment and timed artificial insemination for dairy cow production under heat stress
Daisuke FUNAKOSHI, Hidetoshi SHIOTANI, Makoto SEKI
Volume 70 Issue 1 Pages 30-34
Negative photoperiod induces an increase in the number of ovulations in dairy cattle
Fernando LÓPEZ-GATIUS
Volume 70 Issue 1 Pages 35-41
Serum-free spontaneously immortalized bovine oviduct epithelial cell conditioned medium promotes the early development of bovine in vitro fertilized embryos
Norikazu MIYASHITA, Satoshi AKAGI, Tamas SOMFAI, Yuji HIRAO
Volume 70 Issue 1 Pages 42-48
Technology Report
Capturing temperature changes on the ocular surface along with estrus and ovulation using infrared thermography in Japanese Black cows
Riho OZAKI, Seiji INOUE, Yuki YOROZUI, Rei ICHIKAWA, Naoki YAMADA, Seiya HIGASHI, Shuichi MATSUYAMA, Hiroko TSUKAMURA, Satoshi OHKURA, Yoshihisa UENOYAMA, Yasuhiro MORITA
Volume 70 Issue 1 Pages 49-54