
Aims and Scope
The Journal of Reproduction and Development (JRD) is an international, peer-reviewed Open Access publication, and the official journal of the Society for Reproduction and Development. In six issues per year, JRD publishes basic studies of reproductive biology in vertebrates, including gametogenesis, early embryonic development, placenta development, implantation, reproductive endocrine function and reproductive organ development. JRD also welcomes applied and clinical studies that contribute to the control of reproduction in wild, domestic and laboratory animals, and to the development of new technology to address issues in the field of reproduction. Human clinical case reports are not published by the journal.
After fertilization, dramatic changes in epigenetic regulations and zygotic genome activation (ZGA) occur, eventually leading to a transition from totipotency to pluripotency. However, the regulation of these processes during preimplantation development remains unclear. Yamamoto et al. investigated the functional roles of periodic tryptophan protein 1 (PWP1) in mouse preimplantation embryos (Yamamoto et al. Pwp1 inhibition impairs the development and early lineage commitment of mouse preimplantation embryos, pp. 168–174). The expression of Pwp1 increased during ZGA, and the PWP1 protein was predominantly localized in the nuclei of the inner cell mass at the blastocyst stage (cover photo). Pwp1 knockdown reduced the developmental potential of mouse preimplantation embryos, accompanied by prolonged expression of the ZGA-related genes at the morula stage and altered expression of cell lineage-related genes at the blastocyst stage. These findings suggest that PWP1 is essential for the regulation of early embryonic development.
JRD Information
- Impact factor 2.2 (June 2025)
- Days to the First Decision (all manuscripts): 19 days (2024-2025)
- Gold Open Access Publication
- The publication fees (in the case that US$ 1 is 145 JPY)
Original Articles: 110,000 JPY (Approximately US$ 760)
Technology Reports: 63,000 JPY (Approximately US$ 435)
Reviews: 110,000 JPY (Approximately US$ 760)
Opinions and Hypotheses: 63,000 JPY (Approximately US$ 435)
There are no charges for publication of Color Figures and Supplementary Material. -
JRD Outstanding Paper Award in 2024 Congratulations!
- Chihiro EMORI, Mayo KODANI, Ferheen ABBASI, Masashi MORI, Masahito IKAWA
PABPN1L is required for maternal mRNA degradation after meiosis resumption
Vol. 70 (1): 10-17. DOI: https://doi.org/10.1262/jrd.2023-077 - Ryutaro AIZAWA, Megumi IBAYASHI, Junichiro MITSUI, Satoshi TSUKAMOTO
Lipid droplet formation is spatiotemporally regulated in oocytes during follicular development in mice
Vol. 70 (1): 18-24. DOI: https://doi.org/10.1262/jrd.2023-055 - Atsushi SHIRASAWA, Masafumi HAYASHI, Mayumi SHONO, Atsushi IDETA, Takashi YOSHINO, Katsuhiko HAYASHI
Efficient derivation of embryonic stem cells and primordial germ cell-like cells in cattle
Vol. 70 (2): 82-95. DOI: https://doi.org/10.1262/jrd.2023-087
- Chihiro EMORI, Mayo KODANI, Ferheen ABBASI, Masashi MORI, Masahito IKAWA
Current Issue
Vol. 71 Issue 3 2025
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Original ArticleLow pH induces amiloride-sensitive expression of leukemia inhibitory factor in endometrial cells
Miku OTSUGU, Ayumi MINE, Kurumi FUJIWARA, Ayako ICHIMURA, Keiji YAMAMOTO, Ryo TACHIHARA, Hideaki TOMURA
J Reprod Dev. 2025 Mar 21;71(3):115–123. doi: 10.1262/jrd.2024-105
PDFEnzymatic isolation of porcine preantral follicles impairs oocyte viability and long-term in vitro growthBa Anh My LE, Lien Boi Linh NGUYEN, Phuong Thanh NGUYEN, Ha Nhat Lam VO, Ngoc Song Thu TRAN, Bao Nghi TRAN, Ngoc Thao Vy NGUYEN, Chi Thien LAM, Nhat-Thinh NGUYEN, Van Thuan NGUYEN, Hong-Thuy BUI
J Reprod Dev. 2025 Apr 12;71(3):124–136. doi: 10.1262/jrd.2025-004
PDFCortisol prevents the suppressive effect of LPS on bovine oocyte maturation in vitroSameera PREMARATNE, Mahiro TAMURA, Omowumi ADEMOLA, Yuki MURANISHI, Masafumi TETSUKA
J Reprod Dev. 2025 Apr 12;71(3):137–144. doi: 10.1262/jrd.2024-086
PDFCpG site methylation regulates mouse Rec8 gene promoter activityMei RONG, Na FENG, Jinghuan LI, Wuyun DALAI
J Reprod Dev. 2025 Apr 4;71(3):145–153. doi: 10.1262/jrd.2024-077
PDFMice lacking two testis-specific cytoplasmic poly(A)-binding proteins, PABPC2 and PABPC6, exhibit normal spermatogenesis and fertilityYuka ISONO, Yuko KAKU, Yoshinori KANEMORI, Shin-ichi KASHIWABARA
J Reprod Dev. 2025 Apr 18;71(3):154–160. doi: 10.1262/jrd.2025-012
PDFMechanism of action of IHH in ameliorating thin endometriumLan LUO, Man LUO, Donghong NING, Xi CHEN, Qiuman ZHENG, Qin CAO
J Reprod Dev. 2025 Apr 28;71(3):161–167. doi: 10.1262/jrd.2024-096
PDFPwp1 inhibition impairs the development and early lineage commitment of mouse preimplantation embryosTakuto YAMAMOTO, Atsushi TAKASU, Yasuhiro ISUMI, Satoshi MASHIKO, Daiki SHIKATA, Shinnosuke HONDA, Naojiro MINAMI, Shuntaro IKEDA
J Reprod Dev. 2025 May 3;71(3):168–174. doi: 10.1262/jrd.2024-111
PDFPercentage of follicle number by size over the antral follicle count and its association with subsequent reproductive performance in beef cattleShiori Saito KOHIGASHI, Mizuho UEMATSU, Go KITAHARA, Takeshi OSAWA
J Reprod Dev. 2025 May 8;71(3):175–184. doi: 10.1262/jrd.2024-075
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Technology ReportInexpensive thermal containers and insulation materials prevent deterioration of semen parameters for less than 90 minutes
Erina TAKAYAMA, Hiroki TAKEUCHI, Hideaki YAJIMA, Sayako ENOMOTO, Mito SAKAMOTO, Mikiko NISHIOKA, Ryota TACHIBANA, Tomoaki IKEDA, Eiji KONDO
J Reprod Dev. 2025 Apr 6;71(3):185–190. doi: 10.1262/jrd.2025-001
PDFIn vitro embryo production via ovum pick-up (OPU) and intracytoplasmic sperm injection (ICSI) in pure and crossbred Japanese Hokkaido native poniesM A HANNAN, Hiroyuki WATANABE, Akiko TAKEYAMA, Sakura YOSHIDA, Dorb WUDAMU, Narangerel LKHAGVASUREN, Anthony CLAES, Tom A E STOUT, Soon Hon CHEONG, Shingo HANEDA, Yasuo NAMBO
J Reprod Dev. 2025 May 10;71(3):191–194. doi: 10.1262/jrd.2025-011
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